There are so many different systems out there, what do you prefer? Using a system that is written in the same language like your own software?
I started with the famous Autotools-Collection once. Some years later I found and tried SCons and was amazed. It's so clean and easy in comparison to Autotools-stuff - but to have Python as a dependency for building a project is just a mess. At the moment I am embedding Ruby into my project and I am very confident with Rake.
So it's just another time choose the right one for the right job? What is your opinion?