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Downhill Simplex Method

Is it possible to use Downhill Simplex Method for template matching?Let's say I have 40 landmarks on the edges of an object and I have pixel intesities of normal vectors on these landmarks and I want to use Downhill Simplex Method for strecthing the template I have with iterations after each iteration i will check mean square of errors of the pixels I have in the template object and image I am working on?Anyone got an idea?Thanks

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