I am trying to register a .Net 4.0 compiled binary using regasm utillity. This ComInterOp assemply has to be deployed on a network share, and trying to register from the share fails with the error "Cound not load file or assembly or one of the dependecies". (registration works if the binary is on a local drive). It may be Code access security issue, is there a way to set it for framework 4.0 assembly? I have tried Caspol.exe that ships with 4.0 framework but it did not help.