After reading this post and encountering the same issue (when attempting to build the manifests):
MSB3171: Problem generating manifest. Could not load file or assembly or one of its dependencies. An attempt was made to load a program with an incorrect format.
I would like to know if anyone has had success using .NET Reactor (Encryption/Obfuscation tool) with ClickOnce deployment. I have trawled the net all morning attempting different techniques, and some techniques work with Dotfuscator and Xenocode so I read, but I can't get any love from .NET Reactor.
I really think this message is being received because ClickOnce is attempting to generate a manifest against the encrypted file (of which can't even be opened within .NET Reflector)...
What options do I have here?