Yes, you could create a setup much like the one Misko describes using FlexUnit4. The key is creating an ANT build script that compiles your test runner and then invokes the FlexUnit ANT task on the resulting SWF.
Once you have the ANT build script setup you can jump right into step 4, as outlined in the article.
Getting the ANT build script setup correctly can be a little tricky if you're not familiar with ANT. I found the continuous integration (CI) sample project provided by the FlexUnit4 team to be a great reference. As of this writing, it's available here:
http://opensource.adobe.com/svn/opensource/flexunit/branches/4.x/FlexUnit4SampleCIProject/