The font size I need to match the design I have is 85pt, which is extremely large. In IE6 and IE7, my design is affected because the divs that contain these elements become larger than they normally are, and as a result, elements under these are pushed further down, somewhat breaking the design. I have the height defined for these elements and when I decrease the font size, the elements begin to shrink to the correct size. I've added line-height: 0; to the element and this works in all modern browsers.
Unfortunately, the design I'm working on cannot be shown publicly, but I was hoping to get some insight into other possible techniques that I could try to get the design to render correctly. The height of the parent element is 144px, which includes 10px padding on top and bottom and a top and bottom 1px border.
Unfortunately there's not a lot more that I can add to this, but I'll include whatever info I can if asked.