I use both OOCSS and normal CSS in most of my stylesheets. I don't think that it makes sense to use OOCSS for styling of typography, but for things like columns, boxes and buttons, I think that it does make sense and it can really help to (in my opinion) make the code simpler.
Using a rather contrived (and terrible - classes should describe function, not form) example:
Using OOCSS
a.button {display: block; background-color: red;}
a.border {border: 1px solid orange;}
<a class="button border" href="#">My bordered button</a>
<a class="button" href="#">My normal button</a>
Using normal CSS
a.button_and_border {display: block; background-color: red; border: 1px solid orange;}
a.button_no_border {display: block; background-color: red;}
<a class="button_and_border" href="#">My bordered button</a>
<a class="button_no_border" href="#">My normal button</a>
As you can see, there's less CSS in the OO example, which I personally find easier to read. But I suppose at the end of the day, it's all down to personal preference and coding style :)