Scientific evidence is harder, but there have been articles posted around over the years.. hopefully some web posts will turn up.
Some of the above are suggesting super high contrast -- but in my experience (and I'm thinking I recall it from some of the articles I've read) that this leads to eye strain. You don't want high contrast, you want easy to read .. which may not be the same thing.
Theres also 'fun' and easy to read; I often like to go with the old Amiga style say (white on blue -- good contrast, but not so harsh; it doesn't have to be black and whites.) Also, a variation of that that I've used on Xterms for years is 'white on brown', or really 'white on neutral colour'. The backgtround shoudl not be too light for a lighter colour text, but you can switch to maroon, brown, etc, no problem.
(Years ago in sawfish and other easily configurable window manages, I had them scripted to launch eavh new xterm with a slightly different background colour and minimal frame widgets; minimize distractions, maximize working space in a terminal say, and using white on maroon at the time; the darkness of the background would increase every time a new terminal was opened, so sliding two against each other you could still see the different even without much window decoration or frame width.)
So not scientific, but there are many options open to you. (Doubly important as your eyes age..)
jeff