You could try some CSS along the lines of:
ul#Thumbs li
{
display: inline;
list-style: none;
}
And your buttons:
<ul id="Thumbs">
<li><asp:ImageButton ID="btnVoteUp" Height="16px" Width="16px" runat="server" ImageUrl="images/thumbs_up.gif" CausesValidation="false" CommandArgument='<%#Eval("ID")%>' CommandName="VoteUp" /></li>
<li><asp:ImageButton ID="btnVoteDown" Height="16px" Width="16px" runat="server" CausesValidation="false" ImageUrl="images/thumbs_down.gif" CommandArgument='<%#Eval("ID")%>' CommandName="VoteDown" /></li>
</ul>