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i get a HRESULT 0x80131047 exception in Microsoft Visual Basic 2008 express when debug my application. this happens whenever i click "start debugging" and it doesn't matter what application i load. this is a brand new vista x64 bit machine with a fresh install of VB2008 express.

+1  A: 

This MSDN forum post says that you need to take "special" characters such as slashes, commas, or apostrophes out of your assembly name to avoid that error.

If that doesn't fix it, another suggestion there is to uncheck "Enable the Visual Studio Hosting Process" in the Debug tab.

Mark Rushakoff