+3  A: 

Yes. You would use a MultiBinding along with an IMultiValueConverter.

The MultiBinding help shows an example doing exactly what you're attempting - binding one text box to first + last names.

Reed Copsey
+3  A: 

If you're on WPF 3.5SP1 or above, you don't need to write your own value converter for your use case. Instead, just use StringFormat:

<TextBlock>
  <TextBlock.Text>
    <MultiBinding StringFormat="{}{0}, {1}">
      <Binding Path="LName" />
      <Binding Path="FName"/>
    </MultiBinding>
  </TextBlock.Text>
</TextBlock>

HTH, Kent

Kent Boogaart
Kent: Is there a way to make this binding two-way without a converter, though? This is great for view, but can you edit?
Reed Copsey
@Reed: whoops, I meant `TextBlock`. Updated my post.
Kent Boogaart