No, there isn't a direct easy way to do this. The FAQ addresses this, and provides a kind of workaround:
Deleting by Namespace
While memcached does not support any type of wildcard deleting or deletion by namespace (since there are not namespaces), there are some tricks that can be used to simulate this. They do require extra trips to the memcached servers however.
Example, in PHP, for using a namespace called foo:
$ns_key = $memcache->get("foo_namespace_key");
// if not set, initialize it
if($ns_key===false) $memcache->set("foo_namespace_key", rand(1, 10000));
// cleverly use the ns_key
$my_key = "foo_".$ns_key."_12345";
$my_val = $memcache->get($my_key);
//To clear the namespace do:
$memcache->increment("foo_namespace_key");