The biggest difference is that the GPL requires you to distribute source code if you modify or derive from the code. The Artistic Licence 2.0 does not.
The GPL requires you to ship source code if you make any changes and ship the binary. This is why is it known as a viral license. Companies have been sued to force them to release their source code because of the GPL. See Linksys for one example.
The Artistic License 2.0 does not require code to be redistributed. It is possible to take code licensed in this way and use it in a propreitary solution and not have to ship your modifications. All you would need is to call it something different and give the original author credit. In this way it is much like the BSD license.