A: 
$('#ddlBuyer').click(function() {
    $('div#radios input').attr('checked',false);
});

where div#radios encloses all your radio inputs. I'm assuming ddlBuyer is the id of something that gets clicked.

We can't give an answer in regard to #radTopx since we don't know what it is.

carillonator
Sorry, I was making my way back home.And you are correct, ddlBuyer is indeed a drop down list that gets clicked.
MrDean
A: 

Thank you very much Carillonator, greatly appreciated.

The following code did the trick, I just need to add in the 'input'

ddlBuyer.Attributes.Add("onclick", "$('#tbxProdAC').val(''); $('#txtbxHowMany').val(''); $('#GridView1').remove(); $('#radTopx input').attr('checked',false); ");

Where #radTopx is the radio button list.

MrDean
I believe you are missing some basic understanding of jQuery, adding the "attribute" of onclick is basically the same as adding the .click() event handler from jQuery so you could have done:$('#tbxProdAC').val('');$('#txtbxHowMany').val(''); $('#GridView1').remove();$('#radTopx input').attr('checked',false);all inside the selector function() as carillonator illustrated and thus NOT have to add the attribute.
Mark Schultheiss
OR, perhaps you have a specific reason to do it your way - just pointing out that it is all possible in one function.
Mark Schultheiss
Nope you're right Mark - I do lack a lot of understanding at th is moment in time...unfortunately I need to get some work done asap for demo purposes, I'll then go back and work on best practise and amend the code where appropriate. Thank you for the heads up though Mark, I definitely need pointers in the right direction.
MrDean