Sharepoint File Not Found error

Question

I can't seem to find any relevant information on this exception. It seems to come and go on a specific site, any ideas?

[FileNotFoundException]: File Not Found.
   at Microsoft.SharePoint.ApplicationRuntime.SPLocalFileInfo.get_CacheKey()
   at Microsoft.SharePoint.ApplicationRuntime.GhostedFileTemplateInfo.get_CacheKey()
   at Microsoft.SharePoint.ApplicationRuntime.SPDatabaseFile.GetFileCacheKey(HttpContext context, SPRequestModuleData requestData)
   at Microsoft.SharePoint.ApplicationRuntime.SPDatabaseFile.EnsureCacheKeyAndViewStateHash(HttpContext context, SPRequestModuleData requestData)
   at Microsoft.SharePoint.ApplicationRuntime.SPDatabaseFile.GetVirtualPathProviderCacheKey(HttpContext context, SPRequestModuleData requestData)
   at Microsoft.SharePoint.ApplicationRuntime.SPVirtualFile.GetVirtualPathProviderCacheKey(String virtualPath)
   at Microsoft.SharePoint.ApplicationRuntime.SPVirtualPathProvider.GetCacheKey(String virtualPath)
   at Microsoft.SharePoint.Publishing.Internal.CmsVirtualPathProvider.GetCacheKey(String virtualPath)
   at System.Web.Compilation.BuildManager.GetCacheKeyFromVirtualPath(VirtualPath virtualPath, Boolean& keyFromVPP)
   at System.Web.Compilation.BuildManager.GetVPathBuildResultInternal(VirtualPath virtualPath, Boolean noBuild, Boolean allowCrossApp, Boolean allowBuildInPrecompile)
   at System.Web.Compilation.BuildManager.GetVPathBuildResultWithNoAssert(HttpContext context, VirtualPath virtualPath, Boolean noBuild, Boolean allowCrossApp, Boolean allowBuildInPrecompile)
   at System.Web.Compilation.BuildManager.GetVirtualPathObjectFactory(VirtualPath virtualPath, HttpContext context, Boolean allowCrossApp, Boolean noAssert)
   at System.Web.Compilation.BuildManager.CreateInstanceFromVirtualPath(VirtualPath virtualPath, Type requiredBaseType, HttpContext context, Boolean allowCrossApp, Boolean noAssert)
   at System.Web.UI.PageHandlerFactory.GetHandlerHelper(HttpContext context, String requestType, VirtualPath virtualPath, String physicalPath)
   at System.Web.HttpApplication.MapHttpHandler(HttpContext context, String requestType, VirtualPath path, String pathTranslated, Boolean useAppConfig)
[HttpException]: Exception of type 'System.Web.HttpException' was thrown.
   at System.Web.HttpApplication.MapHttpHandler(HttpContext context, String requestType, VirtualPath path, String pathTranslated, Boolean useAppConfig)
   at System.Web.HttpApplication.MapHandlerExecutionStep.System.Web.HttpApplication.IExecutionStep.Execute()
   at System.Web.HttpApplication.ExecuteStep(IExecutionStep step, Boolean& completedSynchronously)