First C# is not a 'derivitive' of .NET. .NET is not a language, it is an application framework and class library based on the CLR, for which a number of languages exist.
That said, the most compelling reason to use .NET is that it is a well designed class library and a much easier way to develop for Windows than Win32 or MFC. However I personally decided that I'd rather learn a new language learn extensions to an old one, and because C# was designed from the ground up to work with .NET, I suggest that is the language of choice for .NET.
C++/CLI is useful is you want to use .NET with some legacy code, and I have used it for creating Windows Forms GUIs and gluing them to existing application code. Its other raison d'etre is that it is the only .NET language that supports mixed managed and native code in a single load module, so it is good for both performance and reuse of legacy code.
With respect to the number of languages, Microsoft want every Windows application to be based on .NET because it is better for the security and stability of their OS. The only way that will happen is by supporting multiple languages. Think of .NET as an application platform or OS API, and then the question makes less sense; there will be many languages for .NET for the same reason as there are many languages for any platform. Those reasons are many, including commercial advantage, application fit, politics, supporting existing developers, choice and no doubt more.