I have moved an asp.net from the c:-drive to d (well, I did not move it, but first created a new virtual directory on d:\ and then copied the files over and finally removed the old dir from c:). And I restarted the machine.
This worked partially: I can launch aspx-files on the new location, but dependend libararies are no longer found now (although the complete bin-structure was moved over, of course). The import-statements all just use ./-notation, no absolute paths - and since the dir-structure itself hasn't changed (only moved entirely), I don't see a problem there.
But what else could be causing probs then...?