Ok, what i have:
Visual Studio 2010 RC, W7 x64, started a new project type of Silverlight application. Hosting the Silverlight application in a ASP.NET Web Application Project. Silverlight Version 3.0. Added a LinqToSQL Class, a WCF Service, a Winform Tester Application (Project in the Solution) and a few Classes (also as Projects in the Solution).
Yesterday, suddenly i got the 'The breakpoint will not currently be hit. No symbols have been loaded for this document.' message to appear in the IDE, but it only affects the Web Appliaction, i can debug the Silverlight and the Winform App.
What i tried / did to get rid of the message:
Reset Visual Studio Settings, removed all files in every \Temporary ASP.NET Files Folder (there is one for each 32bit/64bit and for Framework 2.0 and 4.0), tried to debug using Visual Studio Integrated Web server - normally i use IIS, in the project output of the solution i deleted every obj and bin folders in every project folder, created a new solution and added all the projects to this new solution, deleted the solution suo file, created a new ASP.NET Web Application to test if it is a VS-installation issue => i can debug this new project/solution, rebooted the machine several times, repaired the vs.net installation, did an IISReset, removed the Web App from IIS, used the Create Virtual Directory Button under Project Properties of the Web App to create a new Web App in IIS, changed the Framework Version of every project from 3.5 to 4.0. Opened the Solution on my second machine=> same behavior, crawled Microsoft Connect for bugs / similar issues. SPENT 7 HOURS.
So, this happens the 2nd time in my life. last time i solved it by deleting Temporary ASP.NET Files Folder, but this time i need your help.
By the way, when i did a little research on the internet, i realized that this issue is discussed so often, i'm sure if we can fix this for me, many others will benefit from solution.