2 ways to do the same in relation to output cache?

Question

On the origin server I have the following caches: http.sys, IIS output cache, asp net output cache, etc

Do these two options do the same? (disable ONLY the asp net output cache)

<caching>
  <outputCache enableOutputCache="false">
  </outputCache>
</caching>

and

response.Cache.SetNoServerCaching();