Reflection is costly because of the many checks the runtime must make whenever you make a request for a method that matches a list of parameters. Somewhere deep inside, code exists that loops over all methods for a type, verifies its visibility, checks the return type and also checks the type of each and every parameter. All of this stuff costs time.
When you execute that method internally theres some code that does stuff like checking you passed a compatible list of parameters before executing the actual target method.
If possible it is always recommended that one caches the method handle if one is going to continually reuse it in the future. Like all good programming tips, it often makes sense to avoid repeating oneself. In this case it would be wasteful to continually lookup the method with certain parameters and then execute it each and everytime.
Poke around the source and take a look at whats being done.