I've successfully got PartCover 2.3 working with VS 2008 on my 64-bit machine.
I'm now trying to get it to work with VS 2010 and NUnit 2.5.3. I've got NUnit using the correct CLR version, but I can't get PartCover to produce any output. All I get is an "empty" report XML file:
<PartCoverReport date="2010-03-30T16:09:05.1009099+01:00" />
How do I get PartCover 2.3 (or 2.2, I guess) to work with NUnit 2.5.3 on .NET 4.0?
There might have been some breaking changes in the profiling API. Atleast they had the major addition of the attach/detach API. http://blogs.msdn.com/davbr/ seems to talk about some of them.
So unless you want to change the sourcecode of the tool yourself, I think you might be out of luck.
If you're not able to get PartCover working, you could try out this new Code Coverage tool developed by JetBrains :] http://blogs.jetbrains.com/dotnet/2010/03/jetbrains-to-launch-dotcover-eap-next-week/ Integrates nicely in Visual Studio and you can toggle highlites on code that's covered.
I have recently completed a portcover fork that will hook into the .NET4 CLR - maybe you could give that a try
I have PartCover and NUnit working properly with VS 2010 and .NET 4.0 on Windows 7 x64.
It was necessary to upgrade to PartCover.NET4 (and recompile it for x86 CPU), and NUnit 2.5.5.
I was originally using NUnit 2.5.4 and could not get it to work with .NET 4.0. I don't know if 2.5.3 works with .NET 4.0. It was also necessary to run the unit tests under nunit-console-x86.exe to force the tests to run in 32 bit, because PartCover only supports 32 bit at this stage because of it's 32 bit COM component.