A few ways you can do this...
Using REGEXP:
wholeNumber = 1934; %# Your number
numberString = num2str(wholeNumber,16); %# Convert to a string
matches = regexp(numberString,'[1-9]','match'); %# Find matches
firstNumber = str2double(matches{1}); %# Convert the first match to a double
Using ISMEMBER:
wholeNumber = 0.04; %# Your number
numberString = num2str(wholeNumber,16); %# Convert to a string
isInSet = ismember(numberString,'123456789'); %# Find numbers that are
%# between 1 and 9
numberIndex = find(isInSet,1); %# Get the first number index
firstNumber = str2double(numberString(numberIndex)); %# Convert to a double
EDIT:
Some discussion of this topic has arisen on one of the MathWorks blogs. Some interesting additional solutions are provided there. One issue that was brought up was having vectorized solutions, so here's one vectorized version I came up with:
numberVector = [1934 0.04 -56];
numberStrings = cellstr(num2str(numberVector(:),16));
firstIndices = regexp(numberStrings,'[1-9]','once');
firstNumbers = cellfun(@(s,i) s(i),numberStrings,firstIndices);