Yes you can ignore those users. The web has always been scriptable and is more so now, and in the near future, than ever before. People who turn js off know what they've done and understand there may be issues with sites because of it. If they know how to turn it off, they know how to turn it back on. Despite all the older articles about this question (and what if they have CSS turned off?), it's just that. From days gone by.
While there may be statistics showing 2%, or 5%, or whatever percent, have js turned off, these are not typical users who visit ecommerce sites on any regular basis and would be surprised if it didn't work for them. It is no longer reasonable for any user to think they can work with such sites without it.
Therefore, with all the ecommerce sites I am contracted for, javascript is considered a given and we have never had any complaints and I never expect any. This is the modern web.