This is what I posted to DirectXDev: ;)
Have you checked how much memory your
application is using? (Be sure to
select the Virtual Memory column in
Task Manager!). My guess would be
memory fragmentation based issues
causing you to, as you suggest, run
out of address space.
It could, however, be a driver bug ...
Does the debug runtime provide any useful information?
Edit: The only other thing I can think of is that the aperture memory has run out. I don't know how this works with PCIExpress but on AGP you can set the aperture size. I've no idea how to check if it is full however. I suspect the error you are seeing is reporting that its full. Are you doing lots of locks with the Discard flag? If so its possible that these are creating tonnes of new allocations in the aperture and is causing you to run out of memory there. This is pure guess work however.
I'd guess that if this is happening with only some of your users it is those on the lower end machines. If things run slowly then you can end up with a lot of data buffered in the command buffer. This will make control laggy and "could", at a guess, lead to the problem you are seeing. You may want to try making sure the command buffer never gets too long. If you make sure the first lock of every frame is done without the discard flag (ie flag set to 0) then this will cause the pipeline to stall until the vertex buffer has been rendered and bring the command buffer back in sync with you. This will cause a slow down as the command buffering will not be able to smooth out frame rate spikes as easily ...
Anyway ... thats just a guess!