First you should not call Directory.GetCurrentDirectory() and concatenate with the file name. The service is running within a web server like IIS or some other type of container, so GetCurrentDirectory will not give you what you are thinking as you found out. (On a quick tangent, as a recommendation in the future if you want to do path combining you should use Path.Combine method as it will handle all the corner cases and be cross platform.)
There are a few ways to do this:
Assembly myAssembly = Assembly.GetAssembly(SomeTypeInAssm.GetType());
string fullFileName = Path.Combine(myAssembly.Location, "MyFile.txt");
The fullFileName should be what you are looking for. Make sure you use a type that is actually in an assembly located and referenced from the directory in question. However be aware because this file in your question in the Program Files area this is a secure area on Vista and higher OS's and you may not have access to do anything but read the file.
Also you could have the installer of the application place in the registry the install path. Then your service if on the same box can pull this information.
Also you could make sure the file you want to load is within the web server environment that is accessable to the WCF service in question.