I would use partial classes. There is no such thing as data layer in DDD-ish code. There is a data tier and it resides on SQL Server. The application code should only contain business layer and some mappings which allow persisting business objects in the mentioned data tier.
Entity Framework is you data access code so you shouldn't built your own. In most cases the database schema would be modified because the model have changed, not the opposite.
That being said, I would discourage you to share your entities in all the layers. I value separation of UI and domain layer. I would use DTO to transfer data in and out of the domain. If I have the necessary freedom, I would even use CQRS pattern to get rid of mapping entities to DTO -- I would simply create a second EF data access project meant only for reading data for the UI. It would be built on top of the same database. You read data through read (anemic -- without business logic) model, but you modify it by issuing commands that are executed against real model implemented using EF and partial methods.
Does this answer your question?