Depending on your application, you'll probably want to use that Font assignment either on text change or focus/unfocus of the textbox in question.
Here's a quick sample of what it could look like (empty form, with just a textbox. Font turns bold when the text reads 'bold', case-insensitive):
public partial class Form1 : Form
{
public Form1()
{
InitializeComponent();
RegisterEvents();
}
private void RegisterEvents()
{
_tboTest.TextChanged += new EventHandler(TboTest_TextChanged);
}
private void TboTest_TextChanged(object sender, EventArgs e)
{
// Change the text to bold on specified condition
if (_tboTest.Text.Equals("Bold", StringComparison.OrdinalIgnoreCase))
{
_tboTest.Font = new Font(_tboTest.Font, FontStyle.Bold);
}
else
{
_tboTest.Font = new Font(_tboTest.Font, FontStyle.Regular);
}
}
}