Scenario is simple to describe, but might have a complex answer:
Imagine a case where you have one write only mysql database. Then you have about 5 or 6 read only databases. The write database has a count for a particular inventory. You have hundreds of thousands of users banging away at this particular inventory item, but only limited quantity. For argument's sake, say 10 items.
What's the best way to ensure that only 10 items get sold? If there is even a 200ms delta between the time the read-only slaves get updated, can't the integrity of the count go stale, thus selling inventory you do not have?
How would you solve/scale this problem?