There are lots of ways to go about setting up e-commerce sites;
If you don't have any experience whatsoever, and don't want to get into anything "complicated", i would suggest going with a customizable web "storefront" hosted by someone else, pre-integrated with credit card processing, etc. There are tons of options for these online. Just search google for "web storefront". Yahoo! even has such a service:
http://smallbusiness.yahoo.com/ecommerce/sellonline.php
Going beyond that, It's pretty easy to integrate with someone like PayPal. They have all sorts of options from the most basic (use a link to send someone to their site with query string parameters to let paypal know what the user wanted to buy):
https://cms.paypal.com/us/cgi-bin/?&cmd=_render-content&content_ID=developer/home
Beyond that level, you will need to signup for a merchant account, or other similar sort of service, like the one offered by authorize.net (who I like):
http://www.authorize.net/
There are components you can buy for most major web development platforms like .NET, JSP, etc. Perfect example is dotnetcart. These components provide out-of-the-box, easy-to-setup integrations with major CC processing companies, as well as out-of-the-box shopping cart implementations:
http://www.dotnetcart.com/
Finally, most merchant services / payment gateways provide web services for direct integration.
PS.) Never ever ever store CC numbers ; )