As several people have noticed, there is a lot of historical baggage about valid formats for variable names. And language designers are always influenced by what they know when they create new languages.
That said, pretty much all of the time a language doesn't allow variable names to begin with numbers is because those are the rules of the language design. Often it is because such a simple rule makes the parsing and lexing of the language vastly easier. Not all language designers know this is the real reason, though. Modern lexing tools help, because if you tried to define it as permissible, they will give you parsing conflicts.
OTOH, if your language has a uniquely identifiable character to herald variable names, it is possible to set it up for them to begin with a number. Similar rule variations can also be used to allow spaces in variable names. But the resulting language is likely to not to resemble any popular conventional language very much, if at all.
For an example of a fairly simple HTML templating language that does permit variables to begin with numbers and have embedded spaces, look at Qompose.