I would use something like this:
http://www.codeproject.com/KB/aspnet/Search_SuggestTextBox.aspx
The good thing about this library is that it is triggered by the text input's onkeyup. This means you can alter their provided JS function to check for the correct key sequence
Maybe something like this:
var shiftDown=false; //Track if SHIFT was the last key pressed.
function searchSuggest(e)
{
var key = window.event ? e.keyCode : e.which;
if (key==40 || key==38)
{
shiftDown=false;
scrolldiv(key);
}
else if (key == 16) // SHIFT WAS PRESSED
{
shiftDown=true;
}
else if (key == 50 && shiftDown) // 2 WAS PRESSED
{
if (searchReq.readyState == 4 || searchReq.readyState == 0)
{
var str = escape(document.getElementById('txtSearch').value);
strOriginal=str;
searchReq.open("GET", 'Result.aspx?search=' + str, true);
searchReq.onreadystatechange = handleSearchSuggest;
searchReq.send(null);
shiftDown=false;
}
}
else
{
shiftDown=false;
}
}