I have run into a few cases where i have been asked to deploy an application (C#, .Net 2.0) to a server and users need to test the application over the network. I have found the following that works with out any hitches other than a warning telling you "hey your running this over a network are you sure you want to do this?":
%systemroot%\Microsoft.NET\Framework\v2.0.50727\caspol -m -cg 1.2 -url \\<Path> FullTrust
Is there a better way of centralizing the application than the above?