It seems like the goal of a lot of ORM tools and custom data access layers (DAO pattern, etc.) is to abstract the database to the point where you could supposedly swap out the entire database system with minimal work.
Following the common DAL patterns is usually a good idea in code, but it seems like it would never be minimal work to swap out a database. (Cost, training, data migration, etc.)
Does anyone have any experience with swapping out one database for another in a large system, and dealing with the implications in code? Is it worth it to worry about abstracting the actual database from your code?