There is only one guaranteed way to determine if an object is serializable. Serialize it and see if the operation succeeds.
I know that seems a bit overkill but there are just so many different ways that serialization can be broken. There are two items in Metadata you can check to see if a type claims serializability (ISerializable and [Serializable]) but this is just a claim. It can and is broken in so many different ways.
The problem is that in the .Net world the act of declaring the ability to be serialized and actually serializing are 2 separate distinct actions. It's perfectly possible (and legal) to do one but not the other. Take this for example
[Serializable]
public class Foo {
public Object Field1;
}
This class claims to be serializable and may very well be. It all depends on the value actually stored in Field1. No amount of metadata inspection on the type will every tell you whether it can actually be serialized. All you can do is try and see if it suceeds.