+1  A: 

Capture the server response using tools like Fiddler and inspect it.

Chetan Sastry
A: 

Use PostbackTriggers

Audlin
any sample of code , please !!!
Alhambra Eidos
A: 

You might be using response.write, server.transfer or similar within updatepanel; avoid that.

refer to http://weblogs.asp.net/leftslipper/archive/2007/02/26/sys-webforms-pagerequestmanagerparsererrorexception-what-it-is-and-how-to-avoid-it.aspx

Mani
A: 

Thanks dud... :)

Jignesh
A: 

Microsoft JScript runtime error: Sys.WebForms.PageRequestManagerParserErrorException: The message received from the server could not be parsed. Common causes for this error are when the response is modified by calls to Response.Write(), response filters, HttpModules, or server trace is enabled. Details: Error parsing near '

Solution

take out button from update panel. then your problem solve.

makhan