The biggest one would be using existing 3rd party controls on your form. Most of the inbuilt controls are pretty easy to reproduce, but if you have a pet 3rd party control, you might have to host that on a regular (non-MVC) aspx page (luckliy this is supported).
Likewise, "web parts"
Also - the feature where ASP.NET uses different html for different clients (mobile, etc) becomes... different; you wouldn't want to do this by hand, but in reality most clients now work with standard html, so it is less of an issue in the first place.
Some things like i18n via resx files need extra work than is in the vanilla MVC template, but the samples are there on the internet.
One point... MVC is licensed only for MS/ASP.NET; so one thing you can't do (without violating the terms, as I understand it) is to run it in mono/Apache - but IANAL.
Now consider the things you can do with MVC, that you can't (or are hard) with vanilla:
- routes instead of pages
- automated input resolution (action arguments)
- proper html control...
- ...enabling jQuery etc for simple AJAX
- separation of concerns
- testability
- IoC/DI
- multiple templating options (not just aspx/ascx)
re input resolution:
public ActionResult Show(string name, int? page, int? pageSize) {...}
will pick "name", "page" and "pageSize" off (any of) the route, query-string or form - so you don't have to spend lots of time picking out request values.
re templates - aspx/ascx aren't the only templating options. For example, see here; or you can write your own if you like... The view is not tied to ASP.NET controls at all.