I've had this intermittent issue when using asp.net. My site is dynamically compiled. Sometimes when I modify a user control my web site complains that it is defined in multiple places. It almost seems like the old control did not get removed from the asp.net temporary files and the updated control is compiled to the same directory so it's defined in multiple places. That would make sense to me except for the fact that I have no control over what is in the Temporary ASP.net Files folder.
I've read that having circular references will cause this. I've made sure that I don't have circular references. Even with the simplest site I've seen this happen.
I've noticed that when using Master Pages this error seems to come up a lot more frequently.
I've read that a hotfix tries to fix this issue but I've gotten this error after applying the hotfix.
If I get the file causing the issue and make an edit to it then the error goes away. Even if I just put a space in the file it will resolve the error.
I can also get the error to resolve sometimes by visiting other pages of the site that might not use the user control and hitting refresh. This does not always work.
If I set the site to debug the error never happens. If I set it so that it comiles on a page by page basis then the error does not happen as much but still happens.
Below is what the error looks like.
Compilation Error Description: An error occurred during the compilation of a resource required to service this request. Please review the following specific error details and modify your source code appropriately.
Compiler Error Message: CS1595: '_ASP.Header_ascx' is defined in multiple places; using definition from 'C:\WINNT\Microsoft.NET\Framework\v1.0.3705\Temporary ASP.NET Files\root\afwew23d\asdfasd423\asdf23.dll'
Edit: I'm using .net 2.0 (3.5) even though the error above says 1.0. I got that error from another source since I can't reproduce the issue every time. But the type of error is the same.
Edit 2: Thanks gisresearch for your research. There was one statement in the link you provided:
One caution even if you have debug=false, is that if you go in and change something in one of your aspx pages, this page will have to be recompiled, but this doesn’t cause an appdomain reload so the whole application is not batch compiled again. This has the effect that the page will now get recompiled separately and get its own dll, so don’t change your aspx pages on a live server too often.
There is a setting in machine.config determining how many recompiles are allowed before the app domain restarts, by default it is set to 15, so after 15 recompilations the app domain will restart, just as it would if you touched the web.config or touched the bin directory.
This seems to say that when debug=false and the site has already been visited and compiled, if you change a page it will only compile that one page. That sounds like it could cause problems. I had thought changing a page or user control would cause the entire app to recompile.