If you want to check for uniqueness in the query (perhaps to ensure that something isn't duplicated), you can include a WHERE clause using the MySQL COUNT() function. E.g.,
SELECT ImageID, UserID FROM TABLEA WHERE COUNT(ImageID) < 2.
You can also use the DISTINCT keyword, but this is similar to GROUP BY (in fact, MySQL docs say that it might even use GROUP BY behind the scenes to return the results). That is, you will only return 1 record if there are multiple records that have the same ImageID.
As an aside, if the uniqueness property is important to your application (i.e. you don't want multiple records with the same value for a field, e.g. email), you can define the UNIQUE constraint on a table. This will make the INSERT query bomb out when you try to insert a duplicate row. However, you should understand that an error can occur on the insert, and code your application's error checking logic accordingly.