I'm working on a program that includes speech synthesis. A few weeks ago, I wrote the introductory
    using (SpeechSynthesizer s = new SpeechSynthesizer())
    {
        s.SetOutputToWaveFile("file.wav");
        s.Speak(textBox1.Text);
    }
program. It worked just fine. I crossed off "research speech synthesis" from my task list and moved on to other parts of the project.
Now I'm writing a real program, and trying to use this same basic block of code.  However, it is now failing on the s.SetOutputToWaveFile call.  It throws a PlatformNotSupportedException, with the following message: "No voice installed on the system or none available with the current security setting."
I'm on 32-bit Vista. As far as I can tell, both programs have the same compiler settings. Note that this is a Winforms app, and not ASP.Net or anything partially trusted. I pulled up the original program in another instance of Visual Studio, and it still works just fine.
Any ideas?
Edit, 11/9/09:
I've added a bounty, and now even just this program:
static void Main(string[] args)
{
    using (SpeechSynthesizer ss = new SpeechSynthesizer())
    {
        ss.Speak("Hello There");
    }
}
fails. I'm guessing that there's some permission or something that I need to set, but I can't find it. My other program - the initial, basic program that does exactly the same as this new one, still works.