I ran some tests. The first method is slightly faster, but not by enough to make any real difference even under heavy use... except when sCompOp could potentially be a very long string. Because the first method searches a fixed-length string, its execution time is very stable no matter how long sCompOp gets, while the second method will potentially iterate through the entire length of sCompOp.
Also, the second method will potentially match invalid strings - "blah blah blah <= blah blah" satisfies the test...
Given that you're likely doing the work of parsing out the operator elsewhere, i doubt either edge case would be a problem. But even if this were not the case, a small modification to the expression would resolve both issues:
/^(>=|<=|<>)$/
Testing code:
function Time(fn, iter)
{
var start = new Date();
for (var i=0; i<iter; ++i)
fn();
var end = new Date();
console.log(fn.toString().replace(/[\r|\n]/g, ' '), "\n : " + (end-start));
}
function IndexMethod(op)
{
return (",>=,<=,<>,".indexOf("," + op + ",") != -1);
}
function RegexMethod(op)
{
return /(>=|<=|<>)/.test(op);
}
function timeTests()
{
var loopCount = 50000;
Time(function(){IndexMethod(">=");}, loopCount);
Time(function(){IndexMethod("<=");}, loopCount);
Time(function(){IndexMethod("<>");}, loopCount);
Time(function(){IndexMethod("!!");}, loopCount);
Time(function(){IndexMethod("the quick brown foxes jumped over the lazy dogs");}, loopCount);
Time(function(){IndexMethod("<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<");}, loopCount);
Time(function(){RegexMethod(">=");}, loopCount);
Time(function(){RegexMethod("<=");}, loopCount);
Time(function(){RegexMethod("<>");}, loopCount);
Time(function(){RegexMethod("!!");}, loopCount);
Time(function(){RegexMethod("the quick brown foxes jumped over the lazy dogs");}, loopCount);
Time(function(){RegexMethod("<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<");}, loopCount);
}
timeTests();
Tested in IE6, FF3, Chrome 0.2.149.30