I have a problem when updating the source of an ASP ListBox in an AJAX update panel.  When I set the source of the ListBox to a large dataset, I would assume it would take a small amount of time to render due to the number of items.  However, when the DataSource is switched at run-time to a smaller set of items, it takes just as long to clear it.  If you go from a small set of items to a small set of items this is lightning fast.  Maybe I'm doing something wrong.  I'm using the Visual Studio 2008 item template for an AJAX 1.0-Enabled ASP.NET 2.0 Web Application.  I downloaded that from Microsoft.  
Here is my code (Full source zip below):
Default.aspx
<%@ Page Language="vb" AutoEventWireup="false" CodeBehind="Default.aspx.vb" Inherits="TestingAJAXComboLoadTimes._Default" %>
<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd">
<html xmlns="http://www.w3.org/1999/xhtml">
<head runat="server">
    <title>Untitled Page</title>
</head>
<body>
    <form id="form1" runat="server">
    <asp:ScriptManager ID="ScriptManager1" runat="server" />
    <asp:UpdatePanel ID="UpdatePanel1" runat="server">
     <ContentTemplate>
      <asp:ListBox ID="myListBox" runat="server" Rows="12" Width="100%" DataTextField="Display"
       DataValueField="Value" AutoPostBack="True" />
      <asp:Button ID="myButton" runat="server" Text="Change List" />
     </ContentTemplate>
    </asp:UpdatePanel>
    </form>
</body>
</html>
Default.aspx.vb
Partial Public Class _Default
    Inherits System.Web.UI.Page
    Private _ListA As IList(Of MyModel) = New List(Of MyModel)
    Private _ListB As IList(Of MyModel) = New List(Of MyModel)
    Protected Sub Page_Load(ByVal sender As Object, ByVal e As System.EventArgs) Handles Me.Load
     LoadData()
     If Not Page.IsPostBack Then
      myListBox.DataSource = _ListA
      myListBox.DataBind()
     End If
    End Sub
    Private Sub LoadData()
     For x As Integer = 0 To 5000
      _ListA.Add(New MyModel("testing A - " & x, x))
     Next
     For x As Integer = 0 To 50
      _ListB.Add(New MyModel("testing B - " & x, x))
     Next
    End Sub
    Private Sub SwitchDataSource()
     If IsALoaded Then
      myListBox.DataSource = _ListB
     Else
      myListBox.DataSource = _ListA
     End If
     IsALoaded = Not IsALoaded
     myListBox.DataBind()
    End Sub
    Private Sub myButton_Click(ByVal sender As Object, ByVal e As System.EventArgs) Handles myButton.Click
     SwitchDataSource()
    End Sub
    Public Property IsALoaded() As Boolean
     Get
      Return CBool(ViewState("IsALoaded"))
     End Get
     Set(ByVal value As Boolean)
      ViewState("IsALoaded") = value
     End Set
    End Property
End Class
MyModel Class (contained within Default.aspx.vb)
Public Class MyModel
    Private _Display As String
    Private _Value As Integer
    Public Sub New(ByVal display As String, ByVal value As Integer)
     _Display = display
     _Value = value
    End Sub
    Public ReadOnly Property Display() As String
     Get
      Return _Display
     End Get
    End Property
    Public ReadOnly Property Value() As Integer
     Get
      Return _Value
     End Get
    End Property
End Class
I didn't modify the web.config file, but here it is for completeness:
<?xml version="1.0"?>
<configuration>
    <configSections>
     <sectionGroup name="system.web.extensions" type="System.Web.Configuration.SystemWebExtensionsSectionGroup, System.Web.Extensions, Version=1.0.61025.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35">
      <sectionGroup name="scripting" type="System.Web.Configuration.ScriptingSectionGroup, System.Web.Extensions, Version=1.0.61025.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35">
       <section name="scriptResourceHandler" type="System.Web.Configuration.ScriptingScriptResourceHandlerSection, System.Web.Extensions, Version=1.0.61025.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35" requirePermission="false" allowDefinition="MachineToApplication"/>
       <sectionGroup name="webServices" type="System.Web.Configuration.ScriptingWebServicesSectionGroup, System.Web.Extensions, Version=1.0.61025.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35">
        <section name="jsonSerialization" type="System.Web.Configuration.ScriptingJsonSerializationSection, System.Web.Extensions, Version=1.0.61025.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35" requirePermission="false" allowDefinition="Everywhere"/>
        <section name="profileService" type="System.Web.Configuration.ScriptingProfileServiceSection, System.Web.Extensions, Version=1.0.61025.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35" requirePermission="false" allowDefinition="MachineToApplication"/>
        <section name="authenticationService" type="System.Web.Configuration.ScriptingAuthenticationServiceSection, System.Web.Extensions, Version=1.0.61025.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35" requirePermission="false" allowDefinition="MachineToApplication"/>
       </sectionGroup>
      </sectionGroup>
     </sectionGroup>
    </configSections>
    <system.web>
     <pages>
      <controls>
       <add tagPrefix="asp" namespace="System.Web.UI" assembly="System.Web.Extensions, Version=1.0.61025.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35"/>
      </controls>
     </pages>
     <!--
          Set compilation debug="true" to insert debugging
          symbols into the compiled page. Because this
          affects performance, set this value to true only
          during development.
    -->
     <compilation debug="true">
      <assemblies>
       <add assembly="System.Web.Extensions, Version=1.0.61025.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35"/>
      </assemblies>
     </compilation>
     <httpHandlers>
      <remove verb="*" path="*.asmx"/>
      <add verb="*" path="*.asmx" validate="false" type="System.Web.Script.Services.ScriptHandlerFactory, System.Web.Extensions, Version=1.0.61025.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35"/>
      <add verb="*" path="*_AppService.axd" validate="false" type="System.Web.Script.Services.ScriptHandlerFactory, System.Web.Extensions, Version=1.0.61025.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35"/>
      <add verb="GET,HEAD" path="ScriptResource.axd" type="System.Web.Handlers.ScriptResourceHandler, System.Web.Extensions, Version=1.0.61025.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35" validate="false"/>
     </httpHandlers>
     <httpModules>
      <add name="ScriptModule" type="System.Web.Handlers.ScriptModule, System.Web.Extensions, Version=1.0.61025.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35"/>
     </httpModules>
    </system.web>
    <system.web.extensions>
     <scripting>
      <webServices>
       <!-- Uncomment this line to customize maxJsonLength and add a custom converter -->
       <!--
      <jsonSerialization maxJsonLength="500">
        <converters>
          <add name="ConvertMe" type="Acme.SubAcme.ConvertMeTypeConverter"/>
        </converters>
      </jsonSerialization>
      -->
       <!-- Uncomment this line to enable the authentication service. Include requireSSL="true" if appropriate. -->
       <!--
        <authenticationService enabled="true" requireSSL = "true|false"/>
      -->
       <!-- Uncomment these lines to enable the profile service. To allow profile properties to be retrieved
           and modified in ASP.NET AJAX applications, you need to add each property name to the readAccessProperties and
           writeAccessProperties attributes. -->
       <!--
      <profileService enabled="true"
                      readAccessProperties="propertyname1,propertyname2"
                      writeAccessProperties="propertyname1,propertyname2" />
      -->
      </webServices>
      <!--
      <scriptResourceHandler enableCompression="true" enableCaching="true" />
      -->
     </scripting>
    </system.web.extensions>
    <system.webServer>
     <validation validateIntegratedModeConfiguration="false"/>
     <modules>
      <add name="ScriptModule" preCondition="integratedMode" type="System.Web.Handlers.ScriptModule, System.Web.Extensions, Version=1.0.61025.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35"/>
     </modules>
     <handlers>
      <remove name="WebServiceHandlerFactory-Integrated"/>
      <add name="ScriptHandlerFactory" verb="*" path="*.asmx" preCondition="integratedMode" type="System.Web.Script.Services.ScriptHandlerFactory, System.Web.Extensions, Version=1.0.61025.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35"/>
      <add name="ScriptHandlerFactoryAppServices" verb="*" path="*_AppService.axd" preCondition="integratedMode" type="System.Web.Script.Services.ScriptHandlerFactory, System.Web.Extensions, Version=1.0.61025.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35"/>
      <add name="ScriptResource" preCondition="integratedMode" verb="GET,HEAD" path="ScriptResource.axd" type="System.Web.Handlers.ScriptResourceHandler, System.Web.Extensions, Version=1.0.61025.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35"/>
     </handlers>
    </system.webServer>
</configuration>
Here is my Google Code project, and my Source Code. Can you tell me why it takes so long to clear the items and set a new list of items?
Thank you,
Scott