In case this is for an independent desktop solution, you can write a simple shell script that executes the following commands. I'm assuming you have the Android SDK installed, as it's required.
To install example.apk located somewhere on your desktop hard drive:
cd location_of_sdk\tools
adb.exe install path_to_apk\example.apk
To uninstall the app:
cd location_of_sdk\tools
adb shell
Inside the adb shell execute:
cd /data/app
ls
This will display the apps installed on the device. Look for the .apk associated with the app you want to uninstall. It'll look something like "com.abc.xyz.apk" - then execute:
rm com.abc.xyz.apk
exit