With Clojure you can get to the speed of Java (with type hints off course) and you can not get faster than java (exept in some very rare cases). I don't know about the other lisps the are maybe the same speed but not faster.
So that said about the standard speed of calls and so on.
Clojure has data structures are not always as fast as possible but the really make up for that with there other properties like thread safety, immutable and fast reading.
To make the data structures faster Rich invented transient with make them mutable in a way that they are still functional (and the are a LOT faster) and he is already working on the next big thing (read about the Emerging Languages camp talk of rich).
Its much easier to write concurrent code with clojure so that is really imported for to make fast programmes.
So the next thing is math. There are three levels of Speed on the JVM. Math with boxed Types,primitiv Types with overflow checking,or without overflow checking. Clojure provides all of those so no limit there.
So the next thing is how fast can you work with Java, if you have to use wrappers you wont perform as good and java calls are used often in most JVM languages. To implement clojure in clojure, clojure needed to add a low level construct so that you can interact with java without any overhead.
So clojure is as fast as it gets on the JVM.
P.S.
Protocols are like really fast multmethods witch are not that generic but the dispatch fast enough to use them in clojure core (and so not depend on java anymore). Look them up the are way cool.