I recently lunched a web site that uses CSS Sprites. It works fine in Firefox 2.0+, Internet Explorer 6+, Safari 3+, Opera 9+ and Chrome 1+, but it looks bad in iPad/iPod/iPhone.
here is a web site http://show.oboz.ua/. It has one sprite image http://show.oboz.ua/css/sprite.png On IPod it looks far from perfect.