ABC.DLL is referenced by your website and it becomes part of it (it is in Bin folder). ASP.NET compiles your website and ABC.DLL is placed in temp location (C:\Windows...\Temporary ASP.NET Filse...). It gets loaded by ASP.NET automatically. You are trying to load ABC.DLL manually from different location (D:\junk\abcabstract\bin\abc.dl). Two assemblies do not match hence you get the error.
To stop this from happening you have to rethink your plugin architecture I guess. Can you give more information?
Update: Why don't you fix it like this:
// Assembly _abc_assembly = Assembly.LoadFile(“c:\junk\abcabstract\bin\abc.dll”);
// ContentAttribute attribute;
// attribute = (ContentAttribute)_abc_assembly.CreateInstance("ABC.TextAttribute");
ContentAttribute attribute = new ContentAttribute();