- Verify the steps used to produce the error
Oftentimes the people reporting the error, or the people reproducing the error, will do something wrong and not end up in the same state, even if they think they are. Try to walk it through with the reporting party. I've had a user INSIST that the admin privileges were not appearing correctly. I tried reproducing the error and was unable to. When we walked it through together, it turned out he was logging in as a regular user in that case.
- Verify the system/environment used to produce the error
I've found many 'irreproducible' bugs and only later discovered that they ARE reproducible on Mac OS (10.4) Running X version of Safari. And this doesn't apply only to browsers and rendering, it can apply to anything; the other applications that are currently being run, whether or not the user is RDP or local, admin or user, etc... Make certain you get your environment as close to theirs as possible before calling it irreproducible.
- Gather Screenshots and Logs
Once you have verified that the user is doing everything correctly and still getting a bug, and that you're doing exactly what they do, and you are NOT getting the bug, then it's time to see what you can actually do about it. Screenshots and logs are critical. You want to know exactly what it looks like, and exactly what was going on at the time.
It is possible that the logs could contain some information that you can reproduce on your system, and once you can reproduce the exact scenario, you might be able to coax the error out of hiding.
Screenshots also help with this, because you might discover that "X piece has loaded correctly, but it shouldn't have because it is dependent on Y" and that might give you a hint. Even if the user can describe what were doing, a screen shot could help even more.
- Gather step-by-step description from the user
It's very common to blame the users, and not trust anything that they say (because they call a 'usercontrol' a 'thingy') but even though they might not know the names of what they're seeing, they will still be able to describe some of the behaviour they are seeing. This includes some minor errors that may have occured a few minutes BEFORE the real error occurred, or possibly slowness in certain things that are usually fast. All these things can be clues to help you narrow down which aspect is causing the error on their machine and not yours.
- Try Alternate Approachs to produce the error
If all else fails, try looking at the section of code that is causing problems, and possibly refactor or use a workaround. If it is possible for you to create a scenario where you start with half the information already there (hopefully in UAT) ask the user to try that approach, and see if the error still occurs. Do you best to create alternate but similar approaches that get the error into a different light so that you can examine it better.