pycrypt is actually a simple AES encrypt/decrypt module built on top of pycrypto like other modules you mention -- note that the latter is transitioning to the pycrypto.org URL as it's changing maintainers, and stable versions and docs are still at the original author's site. In addition to the easier-to-use wrappers you mention, one plus of pycrypto is that a pure-python subset of it is supplied with Google's App Engine, so getting familiar with it would be useful if you ever want to deploy any code there.
The major alternative (another powerful and complex project, like pycrypto) is pyopenssl, which is a fairly regular wrapping (a "thin wrapper", as the author describes it) of OpenSSL (that may be a plus if you're used to coding in C with calls to OpenSSL). An alternative packaging that's complete (comes with the needed libraries) and possibly legally safer (excludes parts on which there are patent disputes or doubts) is distributed by egenix.
Both main projects (pycrypto and pyopenssl) went through long periods of more or less inactivity as the original authors went on to other things, but both are actively developed and maintained again, which is always a good sign.
I am not aware of easy-to-use wrappers on top of pyopenssl (there most likely are, but they haven't been publicized like those on top of pycrypto) and so, if as it seems you do care about ease of use and aren't looking to write wrappers yourself, the ones on top of pycrypto appear to be a better choice.