Give them a breakout, and have them make the finished product. Give them a mockup in image form, and have them reproduce it with the image pieces.
That will show that their CSS and HTML skills are good. If you are looking for Photoshop skills, you could even have them breakout the mockup itself.
As for JavaScript, I would have them implement a few mid-level excercises using whatever libraries you use. For example, have them take the breakout from before, and add slide in effects for all the menu items using jQuery. Or have them implement some tabbed controls.
If you need a JavaScript Guru, I would ask to see any code they have written, and see how it works. have them explain it to you, reflect on their work, and maybe see what could be improved.
Maybe as a bonus, ask them how they would improve your own website, and how they would go about doing it using the aforementioned technologies!
Good luck!