USGS Seamless with a caveat if you want to grab a whole bunch of data at once...
I'll give you one of the best "secrets" that I learned throughout the years after going through many different pains (leeching scripts, manual clicking, etc). It is an old-school trick... contact a real person there!
For example, the best way do get the NED elevation dataset is to contact USGS's Eros group directly at bulkdatainfo_at_usgs.gov
You send them an external drive and after 4 to 8 weeks (usually much less than that) they will send you the entire dataset that you requested.
Of course, you can always try to click away do grab data through their horrible Web UI.
Also, if all you are looking for is some coarse elevation or NASA marble imagery, the test datasets from Spatialite have imagery and elevation for the entire world :)