What should be the best way to load setting from Database?

Question

Hello, how should i load the table "Setting" into an asp.net mvc so that i can use it as a reference setting for the whole application.

Is there anyway to save the memory and usage to do this problem? In my understanding, if i have settings in database, i will have to make the program load the table into a variable, then call out. But is there anyway to save a query from being waste?

im using linq to sql

Thanks